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The ability to pool data is assessed via a hypothesis test (null: no difference in dose-response parameter(s)), where the deviance of the pooled dataset (YT) is added to each individual optimized deviance (Y1, Y2..) and Δ is compared to a Χ2 distribution with df= (number of parameters in each dataset) ‒ (total number of parameters): If these approaches are not sufficient to describe the model fit, more complex approaches must be applied. The purposes are to stimulate research in this field, identify interesting new problems and applications, and foster dialogue and future research collaborations.

Pages: 0

Publisher: Addison Wesley (March 3, 2006)


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