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Legg reported that the excessive hemorrhaging of hemophiliacs most likely arose from a problem with the blood vessels, rather than with the blood itself, though he did admit “the pathology of haemophilia is still buried in the deepest obscurity” (9). This revelation has had at least two beneficial effects: it informs us about the lack of evidence so that we can be more realistic in our expectations and more aware of the uncertainty in medical decision-making, and it exhorts the medical community to search for better evidence. "Nothing should be affirmatively promoted unless there is good evidence of at least some benefit," writes Eddy.

Pages: 602

Publisher: Nabu Press (March 1, 2012)

ISBN: 1276470878

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